INT290437

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

DNA binding (Mef2c, Upf1) cytoplasm (Mef2c, Upf1) cell differentiation (Mef2c)
helicase activity (Upf1) protein complex (Mef2c) RNA binding (Upf1)
Mef2c (Mus musculus)
Upf1 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 10 51.80 Quite High
anesthesia 3 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Left Ventricular Hypertrophy 10 78.88 Quite High
Coronary Heart Disease 13 64.48 Quite High
Fibrosis 10 51.80 Quite High
Hypertrophy 9 42.88 Quite Low
Targeted Disruption 2 35.72 Quite Low
Myocardial Infarction 3 34.40 Quite Low
Stress 8 5.00 Very Low Very Low Very Low
Heart Disease 2 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low
Natriuresis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Transfection of siMEF2C (300 ng/ml) reduced the MEF2C transcripts in NRVMs by approximately 80% (Figure 1A). siMEF2C had no influence in the amounts of MEF2A, MEF2B or MEF2D transcripts (Figure 1B-D).
Gene_expression (Transfection) of siMEF2C Negative_regulation (reduced) of transcripts
1) Confidence 0.02 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2794538 Disease Relevance 0.25 Pain Relevance 0.03

General Comments

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