INT290474

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

DNA binding (MAPK1, Mitf) nucleus (MAPK1, Mitf) protein complex (MAPK1, Mitf)
cell differentiation (Mitf) nucleoplasm (MAPK1) mitochondrion (MAPK1)
MAPK1 (Homo sapiens)
Mitf (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 3 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Melanoma 73 85.88 High High
Injury 1 67.64 Quite High
Cancer 45 5.00 Very Low Very Low Very Low
Metastasis 13 5.00 Very Low Very Low Very Low
Nevus 7 5.00 Very Low Very Low Very Low
Hypoxia 4 5.00 Very Low Very Low Very Low
Hypersensitivity 4 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Aggression 2 5.00 Very Low Very Low Very Low
Breast Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MITF was reported to be regulated by ERK-activating BRAF mutations [20], so we investigated whether differential MITF expression could be explained by using CD200 as a proxy for ERK activation [21].
ERK Regulation (regulated) of MITF
1) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2794539 Disease Relevance 0.15 Pain Relevance 0

General Comments

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