INT290501

Context Info Confidence 0.01 First Reported 2009 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 3 Total Number 4 Disease Relevance 2.82 Pain Relevance 0.14

cell differentiation (H1fnt) chromosome (H1fnt) nucleus (H1fnt) DNA binding (H1fnt)

Anatomy Link Frequency T-cells 2 chest 1 respiratory 1 H1fnt (Mus musculus)

Pain Link Frequency Relevance Heat cytokine 8 75.96 headache 8 64.04 addiction 2 5.00 anesthesia 2 5.00

Disease Link Frequency Relevance Heat Influenza Virus Infection 284 99.20 Leukocytosis 30 98.76 Infection 54 88.32 Sprains And Strains 72 70.68 Headache 8 64.04 Cough 12 63.64 Fever 10 63.36 Emergencies 6 51.28 Pox Virus Infection 46 50.00 Severe Combined Immunodeficiency 36 35.88

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Anatomy

Negation

Speculation

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Significant levels of cross-reactive T-cells recognizing seasonal H1N1/BR and H1N1/NC antigen were also detected, whereas no cross-reaction with pandemic H5N1/VN was induced (P>0.05).

H1N1 Binding (recognizing) of in T-cells

1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2922371 Disease Relevance 0.34 Pain Relevance 0.04

Significant levels of cross-reactive T-cells recognizing seasonal H1N1/BR and H1N1/NC antigen were also detected, whereas no cross-reaction with pandemic H5N1/VN was induced (P>0.05).

H1N1 Binding (recognizing) of in T-cells

2) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2922371 Disease Relevance 0.34 Pain Relevance 0.04

However among patients with acute respiratory illness, features such as a temperature greater than 38°C, rhinorrhea, a normal chest radiograph, and the absence of leukocytosis or significant gastrointestinal symptoms were all positively associated with H1N1(2009) and seasonal influenza infection.

H1N1 Binding (associated) of in respiratory associated with influenza virus infection and leukocytosis

3) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2795196 Disease Relevance 0.78 Pain Relevance 0

Among patients with acute respiratory illness, features such as a temperature greater than 38°C, rhinorrhea, a normal chest radiograph, and the absence of leukocytosis or significant gastrointestinal symptoms were all positively associated with H1N1(2009) and seasonal influenza infection.

H1N1 Binding (associated) of in chest associated with influenza virus infection and leukocytosis

4) Confidence 0.01 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2795196 Disease Relevance 1.37 Pain Relevance 0.06

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