INT290540

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Insr) response to stress (Crh) cytoplasm (Crh)
cytosol (Insr) extracellular space (Crh) extracellular region (Crh)
Anatomy Link Frequency
brain 2
Crh (Mus musculus)
Insr (Mus musculus)
Pain Link Frequency Relevance Heat
amygdala 46 99.88 Very High Very High Very High
Kappa opioid receptor 50 93.04 High High
Dynorphin 49 84.12 Quite High
Opioid 3 50.00 Quite Low
Ventral tegmentum 2 35.64 Quite Low
Dopamine 3 31.96 Quite Low
antagonist 11 5.00 Very Low Very Low Very Low
agonist 10 5.00 Very Low Very Low Very Low
withdrawal 4 5.00 Very Low Very Low Very Low
depression 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 46 56.96 Quite High
Stress 45 46.16 Quite Low
Targeted Disruption 14 5.00 Very Low Very Low Very Low
Depression 3 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Drug Dependence 1 5.00 Very Low Very Low Very Low
Gliosis 1 5.00 Very Low Very Low Very Low
Recurrence 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Control brain sections from mice stereotaxically injected with saline in the BLA show increased KORp-ir induced by CRF (i.c.v) (Fig. 4B).
Positive_regulation (increased) of CRF Positive_regulation (induced) of KORp-ir in brain associated with amygdala
1) Confidence 0.02 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2795205 Disease Relevance 0.06 Pain Relevance 0.64

General Comments

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