INT290553

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.33
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.39
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Crh) signal transduction (Oprk1) extracellular region (Crh)
plasma membrane (Oprk1) response to stress (Crh) cytoplasm (Crh)
Oprk1 (Mus musculus)
Crh (Mus musculus)
Pain Link Frequency Relevance Heat
Kappa opioid receptor 50 100.00 Very High Very High Very High
Dynorphin 49 100.00 Very High Very High Very High
amygdala 46 96.28 Very High Very High Very High
Endogenous opioid 1 94.16 High High
antagonist 11 84.80 Quite High
Opioid 3 75.00 Quite High
agonist 10 74.88 Quite High
withdrawal 4 5.00 Very Low Very Low Very Low
Dopamine 3 5.00 Very Low Very Low Very Low
depression 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 45 92.68 High High
Anxiety Disorder 46 75.00 Quite High
Targeted Disruption 14 49.36 Quite Low
Depression 3 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Drug Dependence 1 5.00 Very Low Very Low Very Low
Gliosis 1 5.00 Very Low Very Low Very Low
Recurrence 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using pharmacological and genetic approaches, we found that the anxiogenic-like effects of Corticotropin Releasing Factor (CRF) were triggered by CRF1-R activation of the dynorphin/kappa opioid receptor (KOR) system.
Positive_regulation (activation) of KOR Positive_regulation (triggered) of Corticotropin Releasing Factor associated with dynorphin and kappa opioid receptor
1) Confidence 0.33 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2795205 Disease Relevance 0.39 Pain Relevance 0.72

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox