INT290594

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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (BDNF, S100B) cell proliferation (S100B) nucleus (S100B)
cytoplasmic membrane-bounded vesicle (BDNF) cytoplasm (S100B)
Anatomy Link Frequency
astrocytes 2
BDNF (Homo sapiens)
S100B (Homo sapiens)
Pain Link Frequency Relevance Heat
antidepressant 45 100.00 Very High Very High Very High
bDMF 5 100.00 Very High Very High Very High
depression 14 57.52 Quite High
sSRI 4 5.00 Very Low Very Low Very Low
fluoxetine 3 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 56 89.92 High High
Neurodegenerative Disease 3 84.84 Quite High
Epilepsy 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Schizophrenia 1 5.00 Very Low Very Low Very Low
Anxiety Disorder 1 5.00 Very Low Very Low Very Low
Blindness 1 5.00 Very Low Very Low Very Low
Obesity 1 5.00 Very Low Very Low Very Low
Cognitive Disorders Amnestic Dementia Delirium 1 5.00 Very Low Very Low Very Low
Manic Depressive Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Antidepressants stimulate the secretion of neurotrophic factors, such as brain derived neurotrophic factor (BDNF).38 Antidepressants also enhance the secretion of S100B by astrocytes via serotonergic systems.15,39-41 Interestingly, in this study, the increase in serum S100B levels in response to treatment with antidepressants was more prominent in nonresponders than in responders.
BDNF Positive_regulation (enhance) of Localization (secretion) of S100B in astrocytes associated with antidepressant and bdmf
1) Confidence 0.08 Published 2008 Journal Psychiatry Investigation Section Body Doc Link PMC2796025 Disease Relevance 0.60 Pain Relevance 0.57

General Comments

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