INT290614

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Context Info
Confidence 0.21
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 3.26
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Th) mitochondrion (Th) oxidoreductase activity (Th)
nucleus (Th) cytoplasm (Th)
Th (Mus musculus)
RLS (Homo sapiens)
Th - V81M (2)
Pain Link Frequency Relevance Heat
Substantia nigra 6 90.64 High High
Dopamine 39 83.28 Quite High
monoamine 3 77.08 Quite High
Catecholamine 3 36.80 Quite Low
drug abuse 3 5.00 Very Low Very Low Very Low
dopamine receptor 3 5.00 Very Low Very Low Very Low
Locus ceruleus 3 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
Ventral tegmentum 3 5.00 Very Low Very Low Very Low
Sciatica 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Restless Legs Syndrome 189 100.00 Very High Very High Very High
Schizophrenia 27 99.84 Very High Very High Very High
Akathisia 12 93.60 High High
Sleep Disorders 12 86.84 High High
Disease 12 5.00 Very Low Very Low Very Low
Psychosis 6 5.00 Very Low Very Low Very Low
Anaemia 3 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Renal Failure 3 5.00 Very Low Very Low Very Low
Hallucination 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, we hypothesized TH to be associated with antipsychotic-induced RLS in schizophrenia patients.
TH Binding (associated) of RLS associated with restless legs syndrome and schizophrenia
1) Confidence 0.21 Published 2009 Journal Psychiatry Investigation Section Body Doc Link PMC2796069 Disease Relevance 0.80 Pain Relevance 0.31
In this study, we investigated the association between antipsychotic-induced RLS and the TH gene Val81Met polymorphism, among schizophrenia patients who took antipsychotics.
TH gene (V81M) Binding (association) of RLS associated with restless legs syndrome and schizophrenia
2) Confidence 0.19 Published 2009 Journal Psychiatry Investigation Section Body Doc Link PMC2796069 Disease Relevance 1.52 Pain Relevance 0
The purpose of this study is to determine whether the TH gene Val81Met polymorphism is associated with antipsychotic-induced RLS.


TH gene (V81M) Binding (associated) of RLS associated with restless legs syndrome
3) Confidence 0.19 Published 2009 Journal Psychiatry Investigation Section Abstract Doc Link PMC2796069 Disease Relevance 0.94 Pain Relevance 0

General Comments

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