INT290630

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Context Info
Confidence 0.07
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.22
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cysltr1) cellular_component (Cysltr1) signal transducer activity (Cysltr1)
Anatomy Link Frequency
upper 1
Cysltr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 9 99.96 Very High Very High Very High
aspirin 44 90.00 High High
Antihistamine 1 81.20 Quite High
corticosteroid 3 76.24 Quite High
Inflammation 11 66.16 Quite High
Inflammatory marker 1 63.08 Quite High
agonist 1 54.80 Quite High
Paracetamol 1 44.40 Quite Low
COX-2 inhibitor 2 43.72 Quite Low
cINOD 2 30.32 Quite Low
Disease Link Frequency Relevance Heat
Asthma 29 98.80 Very High Very High Very High
Chronic Sinusitis 2 97.32 Very High Very High Very High
Nasal Polyps 4 96.24 Very High Very High Very High
Respiratory Disease 84 95.26 Very High Very High Very High
Rhinitis 19 78.04 Quite High
Pressure And Volume Under Development 1 69.24 Quite High
INFLAMMATION 15 66.16 Quite High
Sinusitis 3 55.84 Quite High
Disease 1 27.76 Quite Low
Coronary Artery Disease 1 26.24 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both have been widely prescribed for symptom control in both upper and lower airway of AERD patients.52,53 Several pharmacogenetic LTRA studies have been reported which consider the genetic polymorphisms of CYSLTR1.53 Our previous data have suggested that patients carrying the T allele at CYSLTR1 at -634 C > T required higher doses of cysLTR1 antagonists to control their asthmatic symptoms.42

MANAGEMENT OF CHRONIC RHINOSINUSITIS AND NASAL POLYPOSIS

Positive_regulation (doses) of cysLTR1 in upper associated with asthma, chronic sinusitis, antagonist, nasal polyps and respiratory disease
1) Confidence 0.07 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2796398 Disease Relevance 1.22 Pain Relevance 0.49

General Comments

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