INT290675

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Context Info
Confidence 0.16
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.37
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SPP1, VEGFA) extracellular region (SPP1, VEGFA) cytoplasm (SPP1, VEGFA)
growth (VEGFA) proteinaceous extracellular matrix (VEGFA) cell adhesion (SPP1)
Anatomy Link Frequency
neck 3
head 1
SPP1 (Homo sapiens)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 4 48.96 Quite Low
Chronic pancreatitis 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lung Cancer 2 100.00 Very High Very High Very High
Head & Neck Cancer 2 100.00 Very High Very High Very High
Pancreatic Cancer 100 99.20 Very High Very High Very High
Gastrointestinal Neoplasms 2 96.04 Very High Very High Very High
Metastasis 6 89.96 High High
Adenocarcinoma 10 89.20 High High
Solid Tumor 2 84.20 Quite High
Ovarian Cancer 4 83.20 Quite High
Hypoxia 2 63.92 Quite High
Pancreatitis 4 51.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Osteopontin is an important biomarker in head and neck cancer [20,21] as well as lung cancer [22], and has been shown to be in involved in angiogenesis by acting through the PI3K/Akt pathway to enhance the expression of VEGF [23].
Osteopontin Positive_regulation (enhance) of Gene_expression (expression) of VEGF in neck associated with lung cancer and head & neck cancer
1) Confidence 0.16 Published 2009 Journal J Transl Med Section Body Doc Link PMC2796647 Disease Relevance 1.18 Pain Relevance 0
Osteopontin is an important biomarker in head and neck cancer [20,21] as well as lung cancer [22], and has been shown to be in involved in angiogenesis by acting through the PI3K/Akt pathway to enhance the expression of VEGF [23].
Osteopontin Positive_regulation (enhance) of in head Gene_expression (expression) of VEGF in neck associated with lung cancer and head & neck cancer
2) Confidence 0.06 Published 2009 Journal J Transl Med Section Body Doc Link PMC2796647 Disease Relevance 1.18 Pain Relevance 0

General Comments

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