INT290795

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Context Info
Confidence 0.44
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.22
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Slc2a2) endosome (Slc2a2) transport (Slc2a2)
transmembrane transporter activity (Slc2a2) plasma membrane (Slc2a2) transmembrane transport (Slc2a2)
Anatomy Link Frequency
liver 1
muscle 1
brain 1
Slc2a2 (Mus musculus)
Pain Link Frequency Relevance Heat
Eae 5 99.60 Very High Very High Very High
Central nervous system 14 91.04 High High
Kinase C 18 62.12 Quite High
Inflammatory response 2 44.96 Quite Low
Calcium channel 1 42.12 Quite Low
Dopamine 5 37.72 Quite Low
potassium channel 1 29.64 Quite Low
dexamethasone 2 22.00 Low Low
Hippocampus 10 5.56 Low Low
Inflammation 18 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 38 95.44 Very High Very High Very High
Premature Aging 1 88.80 High High
Diabetes Complications 6 85.60 High High
Diabetes Mellitus 116 82.04 Quite High
Hyperglycemia 10 72.72 Quite High
Alzheimer's Dementia 20 66.72 Quite High
Dementia 15 50.00 Quite Low
INFLAMMATION 20 44.96 Quite Low
Disease 114 26.36 Quite Low
Muscle Disease 10 21.24 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mice with a liver specific deletion of Bmal1 show normal locomotor activity, but the circadian expression of key metabolic genes, such as glucose transporter 2 (glut2), is abolished.
Gene_expression (expression) of glut2 in liver associated with eae
1) Confidence 0.44 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2797305 Disease Relevance 0.09 Pain Relevance 0.05
In the brain, GLUT1, GLUT2 and GLUT5 are expressed predominantly in a cell-specific manner [56-58].
Gene_expression (expressed) of GLUT2 in brain
2) Confidence 0.24 Published 2010 Journal The Open Biochemistry Journal Section Body Doc Link PMC2864432 Disease Relevance 0 Pain Relevance 0.11
-cells via Glut2 glucose transporters, which are not expressed in muscle [35-37].
Neg (not) Gene_expression (expressed) of Glut2 in muscle
3) Confidence 0.08 Published 2010 Journal BMC Physiol Section Body Doc Link PMC2944213 Disease Relevance 1.13 Pain Relevance 0

General Comments

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