INT291011

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Context Info
Confidence 0.08
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.86
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Pomc, ENG) extracellular space (Pomc, ENG) cell-cell signaling (Pomc)
generation of precursor metabolites and energy (Pomc) signal transduction (Pomc) extracellular region (Pomc)
Anatomy Link Frequency
immune cells 2
Pomc (Rattus norvegicus)
ENG (Homo sapiens)
Pain Link Frequency Relevance Heat
IPN 20 100.00 Very High Very High Very High
Inflammation 18 96.32 Very High Very High Very High
Opioid 40 95.72 Very High Very High Very High
Hyperalgesia 22 93.20 High High
Dynorphin 2 92.00 High High
Enkephalin 10 91.44 High High
Pain 16 45.76 Quite Low
Spinal cord 6 31.12 Quite Low
Antinociceptive 8 13.84 Low Low
qutenza 2 11.80 Low Low
Disease Link Frequency Relevance Heat
Inflammatory Pain 20 100.00 Very High Very High Very High
INFLAMMATION 18 96.32 Very High Very High Very High
Hyperalgesia 50 93.20 High High
Nociception 16 65.96 Quite High
Pain 16 45.76 Quite Low
Cold Sores 14 38.32 Quite Low
Bordatella Infection 2 11.04 Low Low
Neuropathic Pain 4 8.00 Low Low
Stress 24 5.00 Very Low Very Low Very Low
Hepatitis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although there was some variability in the control END levels among experimental sets (Fig. 4) this does not seem to predict the efficacy of POMC-MIDGE-NLS in END production.
POMC-MIDGE-NLS Regulation (efficacy) of Gene_expression (production) of END
1) Confidence 0.08 Published 2009 Journal Mol Pain Section Body Doc Link PMC2797781 Disease Relevance 0.51 Pain Relevance 0.32
Effects of POMC-MIDGE-NLS on inflammatory pain and on END content in immune cells
POMC-MIDGE-NLS Regulation (Effects) of Gene_expression (content) of END in immune cells associated with ipn
2) Confidence 0.06 Published 2009 Journal Mol Pain Section Body Doc Link PMC2797781 Disease Relevance 0.35 Pain Relevance 0.59

General Comments

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