INT291074

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Context Info
Confidence 0.45
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 3.77
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (CFB) extracellular region (CFB) plasma membrane (CFB)
Anatomy Link Frequency
adipose tissue 4
fat 2
CFB (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 51 98.56 Very High Very High Very High
Inflammation 24 87.16 High High
cytokine 6 46.84 Quite Low
alcohol 6 5.00 Very Low Very Low Very Low
aspirin 3 5.00 Very Low Very Low Very Low
drug abuse 3 5.00 Very Low Very Low Very Low
Angina 3 5.00 Very Low Very Low Very Low
Inflammatory marker 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 189 99.98 Very High Very High Very High
Insulin Resistance 69 99.40 Very High Very High Very High
Impaired Glucose Tolerance 57 98.56 Very High Very High Very High
Disorder Of Lipid Metabolism 27 97.48 Very High Very High Very High
INFLAMMATION 27 87.16 High High
Weight Loss 51 83.20 Quite High
Endotoxemia 9 80.08 Quite High
Diabetes Mellitus 48 77.40 Quite High
Metabolic Disorder 15 60.96 Quite High
Necrosis 6 49.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inversely, CFB gene expression was increased in omental adipose tissue (0.12 ± 0.08 vs. 0.013 ± 0.007 relative units, P < 0.0001).
Positive_regulation (increased) of Gene_expression (expression) of CFB in adipose tissue associated with obesity
1) Confidence 0.45 Published 2010 Journal Diabetes Section Body Doc Link PMC2797922 Disease Relevance 0.99 Pain Relevance 0
In contrast, CFB gene expression was significantly increased in omental fat but also in association with fasting glucose and triglycerides.
Positive_regulation (increased) of Gene_expression (expression) of CFB in fat
2) Confidence 0.41 Published 2010 Journal Diabetes Section Abstract Doc Link PMC2797922 Disease Relevance 1.29 Pain Relevance 0.08
Adipose tissue CFB gene expression tended to be higher in subjects with insulin resistance (Table 3B), and omental CFB gene expression was significantly associated with fasting glucose and triglycerides (positively) and negatively with HDL cholesterol (Table 3A).
Positive_regulation (higher) of Gene_expression (expression) of CFB in Adipose tissue associated with obesity, insulin resistance and disorder of lipid metabolism
3) Confidence 0.36 Published 2010 Journal Diabetes Section Body Doc Link PMC2797922 Disease Relevance 1.49 Pain Relevance 0.11

General Comments

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