INT291103

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (FFAR1, PDK4) mitochondrion (PDK4) plasma membrane (FFAR1)
carbohydrate metabolic process (PDK4) signal transducer activity (FFAR1)
Anatomy Link Frequency
muscle 2
skeletal muscle 2
FFAR1 (Homo sapiens)
PDK4 (Homo sapiens)
Pain Link Frequency Relevance Heat
lidocaine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Immobilon 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Insulin Resistance 8 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low
Repression 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To test the hypothesis that free fatty acid (FFA) and muscle glycogen modify exercise-induced regulation of PDH (pyruvate dehydrogenase) in human skeletal muscle through regulation of PDK4 expression.


FFA Regulation (regulation) of Gene_expression (expression) of PDK4 in muscle
1) Confidence 0.03 Published 2010 Journal Diabetes Section Abstract Doc Link PMC2797931 Disease Relevance 0 Pain Relevance 0
In conclusion, muscle glycogen and plasma FFAs modify exercise-induced PDH regulation in human skeletal muscle in a nonadditive manner, which might be through glycogen and FFA-mediated regulation of PDK4 expression.
FFA-mediated Regulation (regulation) of Gene_expression (expression) of PDK4 in skeletal muscle
2) Confidence 0.03 Published 2010 Journal Diabetes Section Body Doc Link PMC2797931 Disease Relevance 0 Pain Relevance 0

General Comments

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