INT291124

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.14
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PYGM) small molecule metabolic process (PYGM) transferase activity, transferring glycosyl groups (PYGM)
carbohydrate metabolic process (PYGM) cytoplasm (PYGM)
Anatomy Link Frequency
plasma 1
skeletal muscle 1
leg 1
PYGM (Homo sapiens)
Pain Link Frequency Relevance Heat
lidocaine 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Immobilon 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 3 76.76 Quite High
Insulin Resistance 12 64.88 Quite High
Diabetes Mellitus 3 15.76 Low Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Body Weight 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The possibility that changes in PDK4 protein expression may have mediated the observed association between muscle glycogen and PDH regulation as well as between plasma FFA and PDH regulation is supported by the observation that the highest PDH activation and largest dephosphorylation occurred in the leg and trial with lowest PDK4 protein expression.
Regulation (regulation) of muscle glycogen in leg
1) Confidence 0.02 Published 2010 Journal Diabetes Section Body Doc Link PMC2797931 Disease Relevance 0.08 Pain Relevance 0
Factors responsible for this regulation have been suggested to include changes in plasma FFA concentration (1,12,14), muscle glycogen content (15–17), plasma insulin levels (14,18–20), and intracellular Ca2+ concentration (21,22).
Regulation (changes) of muscle glycogen in plasma
2) Confidence 0.01 Published 2010 Journal Diabetes Section Body Doc Link PMC2797931 Disease Relevance 0.06 Pain Relevance 0
Muscle glycogen and plasma FFA attenuate exercise-induced PDH regulation in human skeletal muscle in a nonadditive manner.
Regulation (regulation) of Muscle glycogen in skeletal muscle
3) Confidence 0.01 Published 2010 Journal Diabetes Section Abstract Doc Link PMC2797931 Disease Relevance 0 Pain Relevance 0

General Comments

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