INT291136

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Context Info
Confidence 0.46
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.36
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (PDP1) small molecule metabolic process (PDP1)
Anatomy Link Frequency
muscle 2
PDP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
lidocaine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Immobilon 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Insulin Resistance 8 83.04 Quite High
Diabetes Mellitus 2 80.80 Quite High
Repression 2 21.60 Low Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the observation that the highest exercise-induced PDHa activity and largest PDH dephosphorylation were present when the muscle glycogen level was only moderately reduced and when FFA remained close to baseline levels (193 ?
Positive_regulation (induced) of Phosphorylation (dephosphorylation) of PDH in muscle
1) Confidence 0.46 Published 2010 Journal Diabetes Section Body Doc Link PMC2797931 Disease Relevance 0.24 Pain Relevance 0
Increases in mitochondrial calcium levels are likely important, since mitochondrial calcium concentration increases during exercise (4,21) and calcium has been shown to activate PDP1 leading to dephosphorylation and activation of PDH (30).
Positive_regulation (leading) of Phosphorylation (dephosphorylation) of PDH
2) Confidence 0.43 Published 2010 Journal Diabetes Section Body Doc Link PMC2797931 Disease Relevance 0.11 Pain Relevance 0

General Comments

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