INT291193

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Context Info
Confidence 0.26
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.87
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Angpt1) signal transduction (Angpt1) extracellular space (Angpt1)
extracellular region (Angpt1) plasma membrane (Angpt1) molecular_function (Angpt1)
Anatomy Link Frequency
myocardium 1
Angpt1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 8 81.84 Quite High
fibrosis 30 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Percutaneous transluminal coronary angioplasty 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 186 99.50 Very High Very High Very High
Myocardial Infarction 138 96.48 Very High Very High Very High
Coronary Artery Disease 10 81.84 Quite High
Ventricular Remodeling 20 50.00 Quite Low
Targeted Disruption 6 40.56 Quite Low
Cv Unclassified Under Development 6 28.00 Quite Low
Heart Rate Under Development 4 8.40 Low Low
Fibrosis 32 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The impairment of myocardial angiogenesis in a diabetic condition has also been associated with compromised signaling mechanisms through the receptors, Flk-1 for VEGF and Tie-2 for Ang-1 (6,28,29).
Ang-1 Binding (associated) of associated with diabetes mellitus
1) Confidence 0.26 Published 2010 Journal Diabetes Section Body Doc Link PMC2797944 Disease Relevance 1.17 Pain Relevance 0.04
Therefore, the therapy might have been effective in correcting the angiogenic machinery directly associated with VEGF and Ang-1 that is impaired in the diabetic myocardium.
Ang-1 Spec (might) Binding (associated) of in myocardium associated with diabetes mellitus
2) Confidence 0.25 Published 2010 Journal Diabetes Section Body Doc Link PMC2797944 Disease Relevance 0.69 Pain Relevance 0

General Comments

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