INT291195

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Context Info
Confidence 0.41
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.29
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Angpt1) signal transduction (Angpt1) extracellular space (Angpt1)
extracellular region (Angpt1) plasma membrane (Angpt1) molecular_function (Angpt1)
Anatomy Link Frequency
myocardium 2
Angpt1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 12 81.44 Quite High
fibrosis 45 39.84 Quite Low
cytokine 6 5.00 Very Low Very Low Very Low
Percutaneous transluminal coronary angioplasty 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Angina 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 279 99.68 Very High Very High Very High
Myocardial Infarction 207 96.96 Very High Very High Very High
Coronary Artery Disease 15 82.32 Quite High
Infarction 3 79.68 Quite High
Cv Unclassified Under Development 9 57.56 Quite High
Ventricular Remodeling 30 50.00 Quite Low
Fibrosis 48 39.84 Quite Low
Heart Rate Under Development 6 37.96 Quite Low
Apoptosis 9 5.00 Very Low Very Low Very Low
Targeted Disruption 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We observed significant reduction in the expression of VEGF and Ang-1 in the diabetic myocardium.
Negative_regulation (reduction) of Gene_expression (expression) of Ang-1 in myocardium associated with diabetes mellitus
1) Confidence 0.41 Published 2010 Journal Diabetes Section Body Doc Link PMC2797944 Disease Relevance 1.01 Pain Relevance 0.07
In the present study, we observed a significant reduction in the expression of Ang-1 (2.2-fold) and Tie-2 (3.1-fold) 4 days after the surgical procedure, in the DS-operated animals compared with CS-operated animals (Fig. 4A and B).
Negative_regulation (reduction) of Gene_expression (expression) of Ang-1
2) Confidence 0.41 Published 2010 Journal Diabetes Section Body Doc Link PMC2797944 Disease Relevance 0.91 Pain Relevance 0
There was a decrease in the expression of VEGF and Ang-1 in the DS compared with CS (Fig. 1B and C).
Negative_regulation (decrease) of Gene_expression (expression) of Ang-1
3) Confidence 0.30 Published 2010 Journal Diabetes Section Body Doc Link PMC2797944 Disease Relevance 0.37 Pain Relevance 0

General Comments

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