INT291202

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.76
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (INS, AKT1) carbohydrate metabolic process (INS, AKT1) cell differentiation (AKT1)
nucleoplasm (AKT1) transport (AKT1) protein modification process (AKT1)
INS (Homo sapiens)
AKT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 39 84.08 Quite High
Inflammatory stimuli 5 82.96 Quite High
Inflammation 26 75.20 Quite High
Inflammatory mediators 2 25.76 Quite Low
tolerance 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 106 86.88 High High
INFLAMMATION 33 82.96 Quite High
Insulin Resistance 10 56.88 Quite High
Cancer 5 50.00 Quite Low
Necrosis 3 50.00 Quite Low
Diabetes Mellitus 8 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Impaired Glucose Tolerance 1 5.00 Very Low Very Low Very Low
Dislocations 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One important finding of our study is that Tpl2 was not required for the activation of ERK or PKB pathways by insulin.
Neg (not) Positive_regulation (required) of insulin Positive_regulation (activation) of PKB
1) Confidence 0.01 Published 2010 Journal Diabetes Section Body Doc Link PMC2797946 Disease Relevance 0.76 Pain Relevance 0.29

General Comments

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