INT291347

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TXK, CXCR4, EPHB2) cytoplasm (TXK, CXCR4) cytoplasmic membrane-bounded vesicle (CXCR4)
nucleus (TXK) DNA binding (TXK) signal transducer activity (CXCR4)
TXK (Homo sapiens)
CXCR4 (Homo sapiens)
EPHB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 99 70.72 Quite High
Inflammation 10 5.00 Very Low Very Low Very Low
antagonist 9 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 156 95.36 Very High Very High Very High
Pituitary Cancer 2 84.44 Quite High
Ovarian Cancer 85 69.20 Quite High
Apoptosis 2 63.44 Quite High
Breast Cancer 10 8.24 Low Low
Metastasis 18 5.00 Very Low Very Low Very Low
INFLAMMATION 13 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 12 5.00 Very Low Very Low Very Low
Leukemia 10 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
More recently, several studies proposed that CXCR4-dependent activation of ERK1/2 was mediated by transactivation of tyrosine kinase receptors.
Positive_regulation (transactivation) of tyrosine kinase Positive_regulation (mediated) of CXCR4-dependent Positive_regulation (activation) of ERK1
1) Confidence 0.02 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC2798669 Disease Relevance 0.61 Pain Relevance 0.13

General Comments

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