INT291358

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Context Info
Confidence 0.20
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.11
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (CXCL12, CXCR7) signal transduction (CXCL12) extracellular space (CXCL12)
extracellular region (CXCL12) plasma membrane (CXCR7) cytoplasm (CXCR7)
CXCL12 (Homo sapiens)
CXCR7 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 99 98.04 Very High Very High Very High
Inflammation 10 5.00 Very Low Very Low Very Low
antagonist 9 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 1 64.88 Quite High
Cancer 156 50.04 Quite High
Ovarian Cancer 85 50.00 Quite Low
Malignant Neoplastic Disease 12 47.12 Quite Low
Germ Cell And Embryonal Neoplasms 1 31.04 Quite Low
Metastasis 18 16.44 Low Low
Endometrial Cancer 3 7.36 Low Low
INFLAMMATION 13 5.00 Very Low Very Low Very Low
Leukemia 10 5.00 Very Low Very Low Very Low
Breast Cancer 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It was suggested that the key role of CXCR7 is to bind and internalize CXCL12 thereby controlling the level of the diffusible chemokine in the extracellular space [108].
CXCL12 Binding (bind) of CXCR7 associated with chemokine
1) Confidence 0.20 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC2798669 Disease Relevance 0.11 Pain Relevance 0.09

General Comments

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