INT291446

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Bdnf) cytoplasmic membrane-bounded vesicle (Bdnf)
Anatomy Link Frequency
pyramidal neurons 2
Bdnf (Mus musculus)
Ltp (Mus musculus)
Pain Link Frequency Relevance Heat
Long-term potentiation 8 100.00 Very High Very High Very High
Pyramidal cell 20 96.00 Very High Very High Very High
Hippocampus 4 87.72 High High
Glutamate receptor 2 58.76 Quite High
potassium channel 3 50.00 Quite Low
nMDA receptor 9 16.48 Low Low
Amygdala 5 9.96 Low Low
action potential 20 5.00 Very Low Very Low Very Low
Ventral tegmentum 10 5.00 Very Low Very Low Very Low
substantia nigra 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 1 11.40 Low Low
Schizophrenia 14 5.00 Very Low Very Low Very Low
Ataxia 8 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low
Epilepsy 6 5.00 Very Low Very Low Very Low
Headache 5 5.00 Very Low Very Low Very Low
Manic Depressive Disorder 4 5.00 Very Low Very Low Very Low
Anorexia 3 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, these findings suggest that BDNF might facilitate the induction of LTP by inhibiting SK-mediated currents possibly through the reduction of SK2 surface expression in CA1 pyramidal neurons [96, 117].
BDNF Positive_regulation (facilitate) of Positive_regulation (induction) of LTP in pyramidal neurons associated with pyramidal cell and long-term potentiation
1) Confidence 0.02 Published 2008 Journal Cell Mol Life Sci Section Body Doc Link PMC2798969 Disease Relevance 0 Pain Relevance 0.26

General Comments

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