INT291672

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Context Info
Confidence 0.66
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.63
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Alox5) nuclear envelope (Alox5) oxidoreductase activity (Alox5)
nucleus (Alox5) cytoplasm (Alox5)
Anatomy Link Frequency
myocardial cells 1
Alox5 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 5 98.86 Very High Very High Very High
ischemia 2 84.76 Quite High
Central nervous system 10 76.28 Quite High
depression 2 58.72 Quite High
cerebral cortex 2 44.88 Quite Low
Hippocampus 9 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 5 98.86 Very High Very High Very High
Cv Unclassified Under Development 1 84.76 Quite High
Disease 1 83.32 Quite High
Brain Hemorrhage 1 79.84 Quite High
Aging 39 78.60 Quite High
Depression 2 58.72 Quite High
Neurodegenerative Disease 1 50.96 Quite High
Increased Venous Pressure Under Development 1 42.52 Quite Low
Lifespan 1 17.52 Low Low
Urological Neuroanatomy 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, in the heart, that is, myocardial cells, drugs such as statins and thiazolidinediones trigger anti-inflammatory processes and increase the production of anti-inflammatory lipoxins depending on 5-LOX, particularly the status of 5-LOX phosphorylation [15, 23].
   5-LOX gene expression is regulated by epigenetic mechanisms including modifications of DNA methylation [1, 24–26]. 
Phosphorylation (phosphorylation) of 5-LOX in myocardial cells associated with inflammation
1) Confidence 0.66 Published 2009 Journal Neural Plasticity Section Body Doc Link PMC2801004 Disease Relevance 0.63 Pain Relevance 0.28

General Comments

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