INT291692

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Context Info
Confidence 0.32
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.57
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Rxra) enzyme binding (Rxra) DNA binding (Rxra)
transcription factor binding (Rxra)
Rxra (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 6 51.40 Quite High
cINOD 7 38.00 Quite Low
agonist 4 13.52 Low Low
Inflammation 10 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metabolic Syndrome 3 80.64 Quite High
Insulin Resistance 7 79.56 Quite High
Confusion 3 68.36 Quite High
Obesity 54 66.64 Quite High
Bladder Cancer 3 48.60 Quite Low
INFLAMMATION 14 37.44 Quite Low
Colon Cancer 1 25.76 Quite Low
Dyslipidemia /

Combined Dyslipidemia

1 24.24 Low Low
Hypertension 1 23.12 Low Low
Overweight 1 21.68 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, other mutations can alter heterodimerization of RXR with certain partners.
Regulation (alter) of RXR Binding (heterodimerization) of
1) Confidence 0.32 Published 2009 Journal PPAR Research Section Body Doc Link PMC2801013 Disease Relevance 0 Pain Relevance 0
Our laboratory has created and tested an engineered RXR/PPAR heterodimer consist of mouse RXR?
Regulation (tested) of RXR Binding (heterodimer) of
2) Confidence 0.23 Published 2009 Journal PPAR Research Section Body Doc Link PMC2801013 Disease Relevance 0.07 Pain Relevance 0.03
Our laboratory has created and tested an engineered RXR/PPAR heterodimer consist of mouse RXR?
Regulation (/) of RXR Binding (heterodimer) of
3) Confidence 0.23 Published 2009 Journal PPAR Research Section Body Doc Link PMC2801013 Disease Relevance 0.07 Pain Relevance 0.03
trans-activating ability in the presence of a synthetic ligand, affecting its ability to recruit cofactors, ligands, and RXR?
Regulation (affecting) of RXR Binding (ligands) of
4) Confidence 0.03 Published 2010 Journal PPAR Research Section Body Doc Link PMC2943117 Disease Relevance 0.44 Pain Relevance 0

General Comments

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