INT29173

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Context Info
Confidence 0.49
First Reported 1987
Last Reported 2007
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.52
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Mention Frequency
Sertoli cell 2


Pain Term Frequency Confidence Heat
opiate 1 92.80 High High
Opioid 1 89.60 High High
Enkephalin 1 86.40 High High
abdominal pain 3 14.24 Low Low
backache 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Term Frequency Confidence Heat
Cystadenoma 16 89.60 High High
Pancreatic Cancer 3 88.88 High High
Metastasis 2 87.56 High High
Adenocarcinoma 6 85.36 High High
Cancer 21 83.84 Quite High
Malignant Neoplastic Disease 7 80.12 Quite High
Cicatrix 2 71.20 Quite High
Cyst 2 65.20 Quite High
Adenoma 10 50.00 Quite Low
Abdominal Pain 3 14.24 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-inhibin, MUC-1 and MUC-6 [1,8], and negative for ?
Positive_regulation (negative) of Neg (negative) Gene_expression ([1,8) of inhibin
1) Confidence 0.49 Published 2007 Journal World J Surg Oncol Section Body Doc Link PMC1821026 Disease Relevance 1.52 Pain Relevance 0
Beta-endorphin alone did not alter basal inhibin accumulation in primary Sertoli cell-enriched cultures, however it did significantly reduce FSH-induced inhibin production and adenylyl cyclase activity but had no effect on forskolin-stimulated inhibin accumulation or adenylyl cyclase activity.
Positive_regulation (-) of Gene_expression (production) of inhibin in Sertoli cell
2) Confidence 0.45 Published 1987 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 2825689 Disease Relevance 0 Pain Relevance 0.27

General Comments

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