INT291786

Context Info Confidence 0.01 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.03

cytoplasm (GOPC, Gnat3) signal transduction (Gnat3) Golgi apparatus (GOPC) plasma membrane (GOPC) GTPase activity (Gnat3) signal transducer activity (Gnat3)

GOPC (Homo sapiens) Gnat3 (Mus musculus)

Pain Link Frequency Relevance Heat Potency 2 57.28 Bioavailability 4 5.00 tolerance 3 5.00 Glutamate 2 5.00 Angina 1 5.00 ischemia 1 5.00 alcohol 1 5.00

Disease Link Frequency Relevance Heat Increased Venous Pressure Under Development 2 5.00 Coronary Artery Disease 2 5.00 Targeted Disruption 1 5.00 Angina 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Surprisingly, Alda-1 did not stimulate but inhibited GTN denitration by both ALDH2 variants (Fig. 5).

Fig Negative_regulation (inhibited) of Gene_expression (denitration) of GTN

1) Confidence 0.01 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2801295 Disease Relevance 0 Pain Relevance 0.03

General Comments

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