INT291797

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Context Info
Confidence 0.15
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.33
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CA2, MYLK) cytoplasm (CA2, MYLK) extracellular space (CA2)
lyase activity (CA2) cytoskeleton (MYLK) enzyme binding (MYLK)
Anatomy Link Frequency
smooth muscle 2
CA2 (Homo sapiens)
MYLK (Homo sapiens)
Pain Link Frequency Relevance Heat
Serotonin 5 88.28 High High
agonist 1 87.08 High High
cva 54 73.64 Quite High
substance P 2 26.48 Quite Low
bradykinin 1 25.88 Quite Low
Inflammation 12 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 54 73.64 Quite High
Spasticity 8 69.60 Quite High
Coronary Vasospasm 7 56.64 Quite High
Spontaneous Remission 1 36.68 Quite Low
Atherosclerosis 9 33.92 Quite Low
Muscular Spasm 8 12.68 Low Low
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 12 5.00 Very Low Very Low Very Low
Coronary Artery Disease 7 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The Ca2+/calmodulin complex then activates MLCK, with subsequent phosphorylation of myosin light chain.60) Thus, the more intracellular Ca2+ concentration is increased, the more contraction of vascular smooth muscle will occur.
Ca2 Binding (complex) of in smooth muscle Positive_regulation (activates) of MLCK
1) Confidence 0.15 Published 2009 Journal Korean Circulation Journal Section Body Doc Link PMC2801457 Disease Relevance 0.33 Pain Relevance 0.19

General Comments

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