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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.67
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Txn2) mitochondrion (Txn2) nucleolus (Txn2)
Txn2 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 9 62.96 Quite High
Angina 2 19.52 Low Low
fibrosis 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Heart Disease 4 99.46 Very High Very High Very High
Diabetic Cardiomyopathies 14 87.16 High High
Insulin Resistance 4 84.40 Quite High
Diabetes Mellitus 135 83.92 Quite High
Myocardial Infarction 44 76.64 Quite High
Cardiovascular Disease 18 72.72 Quite High
Chronic Renal Failure 1 70.64 Quite High
Reperfusion Injury 2 63.72 Quite High
Cv Unclassified Under Development 5 62.96 Quite High
Stress 41 60.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vivo administration of the antioxidant tempol (1 mmol/l in drinking water) for a period of 4-weeks to mice rendered insulin-resistant by deficiency of the insulin-sensitive GLUT4 transporter significantly and potently attenuated cardiac hypertrophy in concert with tempol up-regulated ventricular expression of thioredoxin-2 (confirming an antioxidant action) [101].
Regulation (regulated) of Gene_expression (expression) of thioredoxin-2 associated with coronary heart disease
1) Confidence 0.04 Published 2008 Journal Current Cardiology Reviews Section Body Doc Link PMC2801857 Disease Relevance 1.67 Pain Relevance 0.06

General Comments

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