INT291839

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Context Info
Confidence 0.36
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 1.13
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (Krt4) embryo development (Krt4)
Anatomy Link Frequency
wing cell 2
epithelial cells 2
Krt4 (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 8 76.36 Quite High
Inflammation 36 69.72 Quite High
Inflammatory response 4 59.20 Quite High
cytokine 4 5.00 Very Low Very Low Very Low
eye pain 4 5.00 Very Low Very Low Very Low
local anesthetic 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cleidocranial Dysplasia 28 90.44 High High
Corneal Opacity 4 73.68 Quite High
INFLAMMATION 40 69.72 Quite High
Metaplasia 4 55.36 Quite High
Mucositis 44 50.00 Quite Low
Apoptosis 4 24.48 Low Low
Toxicity 8 21.28 Low Low
Injury 4 10.24 Low Low
Disorders Of The Lacrimal System 8 5.00 Very Low Very Low Very Low
Vomiting 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the left eye of patient 2, epithelial cells expressing K4 were present sporadically in the superficial and wing cell layers.
Gene_expression (expressing) of K4 in wing cell
1) Confidence 0.36 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2802292 Disease Relevance 0.25 Pain Relevance 0
In the left eye of patient 2, epithelial cells expressing K4 were present sporadically in the superficial and wing cell layers.
Gene_expression (expressing) of K4 in wing cell
2) Confidence 0.31 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2802292 Disease Relevance 0.25 Pain Relevance 0
Cells lacking both K12 and K4 were observed in all layers of the epithelium in both eyes of patient 2 and the right eye of patient 3.


Neg (lacking) Gene_expression (lacking) of K4 in epithelium
3) Confidence 0.31 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2802292 Disease Relevance 0.24 Pain Relevance 0
All corneal epithelial cells thus express K12, and all conjunctival epithelial cells express K4 [28].
Gene_expression (express) of K4 in epithelial cells
4) Confidence 0.28 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2802292 Disease Relevance 0.40 Pain Relevance 0.17

General Comments

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