INT291889

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Context Info
Confidence 0.45
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.39
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Pax6) nucleus (Pax6) intracellular (Pax6)
DNA binding (Pax6) cytoplasm (Pax6)
Pax6 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 8 14.64 Low Low
cINOD 10 5.00 Very Low Very Low Very Low
Eae 6 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Anterior cingulate cortex 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 11 93.76 High High
Autism 6 74.24 Quite High
Infection 17 72.56 Quite High
Schizophrenia 8 68.76 Quite High
INFLAMMATION 11 5.00 Very Low Very Low Very Low
Adhesions 7 5.00 Very Low Very Low Very Low
Congenital Anomalies 6 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Influenza Virus Infection 5 5.00 Very Low Very Low Very Low
Targeted Disruption 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Transition from RG to IPC is associated with upregulation of TBR2, a T-domain transcription factor, and downregulation of PAX6 (28–30).
Negative_regulation (downregulation) of PAX6
1) Confidence 0.45 Published 2010 Journal mBio Section Body Doc Link PMC2953007 Disease Relevance 0.39 Pain Relevance 0
Analysis of RNA synthesis in RPCs using RT-PCR revealed marked down-regulation of Pax6, Hes1, B3-tubulin, DCX and partial down-regulation of nestin and Sox2 (Fig. 4).
Negative_regulation (down-regulation) of Pax6
2) Confidence 0.32 Published 2008 Journal J Ocul Biol Dis Infor Section Body Doc Link PMC2802414 Disease Relevance 0 Pain Relevance 0

General Comments

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