INT291904

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Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NR1H2) nucleus (NR1H2) DNA binding (NR1H2)
cytoplasm (NR1H2)
NR1H2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 6 96.00 Very High Very High Very High
Paracetamol 5 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 3 62.96 Quite High
Nicotine Addiction 11 5.00 Very Low Very Low Very Low
Cancer 9 5.00 Very Low Very Low Very Low
Bladder Cancer 8 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Transitional Cell Carcinoma 2 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Adenoma 2 5.00 Very Low Very Low Very Low
Nephrotoxicity 2 5.00 Very Low Very Low Very Low
Lymphatic System Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In two cell lines both deficient in NER and one expressing CYP1A2 and NAT2, 2,6-DMA and 3,5-DMA were cytotoxic at dose levels of 100 ?
Negative_regulation (deficient) of Gene_expression (one) of NER
1) Confidence 0.13 Published 2010 Journal Carcinogenesis Section Body Doc Link PMC2802674 Disease Relevance 0.06 Pain Relevance 0.08

General Comments

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