INT291914

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.34
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.36
Pain Relevance 0.84

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ros1) cell proliferation (Ros1) signal transduction (Ros1)
plasma membrane (Ros1) kinase activity (Ros1)
Anatomy Link Frequency
hepatocytes 2
Ros1 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 69 96.16 Very High Very High Very High
lidocaine 26 69.68 Quite High
acular 27 66.96 Quite High
diclofenac 22 65.84 Quite High
antagonist 1 61.88 Quite High
aspirin 1 58.16 Quite High
depression 5 41.92 Quite Low
anesthesia 6 21.12 Low Low
local anesthetic 6 7.48 Low Low
ischemia 15 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aids-related Complex 9 99.16 Very High Very High Very High
Death 5 98.72 Very High Very High Very High
Cataract 48 98.04 Very High Very High Very High
Toxicity 18 90.00 High High
Injury 40 88.44 High High
Stress 8 87.60 High High
Noise-induced Hearing Loss 26 54.88 Quite High
Shock 5 50.00 Quite Low
Apoptosis 9 44.96 Quite Low
Depression 5 41.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
If LEC loss and the accumulation of cortical nuclear fragments and ROS are instrumental in ARC progress, exogenous agents capable of damaging LECs, and inducing oxidative damage, would be expected to produce the same series of events in an accelerated fashion.
Negative_regulation (loss) of Localization (accumulation) of ROS associated with aids-related complex
1) Confidence 0.34 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2925908 Disease Relevance 0.56 Pain Relevance 0
The anti-oxidants serve to reduce harmful effects of the excessive release of free radicals (such as reactive oxygen species, ROS) which occurs during and after the noise exposure.
Negative_regulation (reduce) of Localization (release) of ROS
2) Confidence 0.30 Published 2010 Journal J Occup Med Toxicol Section Body Doc Link PMC2936911 Disease Relevance 0.05 Pain Relevance 0.06
Vascular relaxation in the ROS scavenger pretreatment
Negative_regulation (relaxation) of Localization (pretreatment) of ROS
3) Confidence 0.20 Published 2010 Journal Korean Journal of Anesthesiology Section Body Doc Link PMC2946038 Disease Relevance 0.15 Pain Relevance 0.10
Vascular relaxation in the ROS scavenger pretreatment
Negative_regulation (relaxation) of Localization (pretreatment) of ROS
4) Confidence 0.12 Published 2010 Journal Korean Journal of Anesthesiology Section Body Doc Link PMC2926425 Disease Relevance 0.16 Pain Relevance 0.12
Recently, it has been reported that the APAP-induced reactive oxygen species (ROS) generation followed by lipid peroxidation in mouse primary hepatocytes induced cell death, and pretreatment with melatonin known as a potent antioxidant suppressed the increase in ROS and lipid peroxides, resulting in prevention of cell death [58].
Negative_regulation (suppressed) of Localization (increase) of ROS in hepatocytes associated with paracetamol and death
5) Confidence 0.04 Published 2010 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2803132 Disease Relevance 0.45 Pain Relevance 0.56

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox