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Context Info
Confidence 0.26
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.15
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (FOXA2) DNA binding (FOXA2) transcription factor binding (FOXA2)
cytoplasm (FOXA2)
FOXA2 (Homo sapiens)
Pain Link Frequency Relevance Heat
abdominal pain 3 34.92 Quite Low
imagery 5 10.32 Low Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
pain pelvic 1 5.00 Very Low Very Low Very Low
nud 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endometrial Cancer 153 97.64 Very High Very High Very High
Gynecomastia 21 95.76 Very High Very High Very High
Kartagener Syndrome 1 94.56 High High
Movement Disorders 1 91.48 High High
Congenital Anomalies 4 79.36 Quite High
Apoptosis 16 77.88 Quite High
Aneuploidy 3 60.64 Quite High
Cancer 95 59.68 Quite High
Malignant Neoplastic Disease 21 59.36 Quite High
Adenocarcinoma 14 53.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mutations in genes responsible for lateralization and polarizations as well as alterations in the TGF-B family gene, Nodal and in the transcription factor HNF-3B are possibly involved in the process [5].
Regulation (alterations) of HNF-3B
1) Confidence 0.26 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2803176 Disease Relevance 0.90 Pain Relevance 0
Intestinal trefoil protein, TFF3, AGR2 developmental gene, estrogen-regulated genes (MGB2, LTF, END1, MMP11), FOXA2, and MSX2 were significantly up-regulated in endometrioid endometrial carcinomas, while increased expression of FOLR, genes involved in the regulation of mitotic spindle checkpoint (STK15, BUB1, CCNB2), IGF2, PTGS1 and p16 were seen in non-endometrioid endometrial carcinomas.
Regulation (regulated) of FOXA2 associated with endometrial cancer
2) Confidence 0.20 Published 2010 Journal Obstetrics and Gynecology International Section Body Doc Link PMC2846683 Disease Relevance 1.25 Pain Relevance 0

General Comments

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