INT291964

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Context Info
Confidence 0.08
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.39
Pain Relevance 1.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Grin2b) peptidase activity (Phex) Golgi apparatus (Phex)
endoplasmic reticulum (Phex) plasma membrane (Grin2b) embryo development (Grin2b)
Phex (Mus musculus)
Grin2b (Mus musculus)
Pain Link Frequency Relevance Heat
Central grey 77 100.00 Very High Very High Very High
Analgesic 7 98.04 Very High Very High Very High
Inflammation 20 97.48 Very High Very High Very High
Thermal hyperalgesia 7 89.76 High High
Pain 17 82.12 Quite High
substance P 1 55.04 Quite High
bradykinin 1 54.00 Quite High
Serotonin 1 52.80 Quite High
nMDA receptor 11 50.00 Quite Low
Hyperalgesia 1 38.48 Quite Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 77 100.00 Very High Very High Very High
Injury 17 100.00 Very High Very High Very High
INFLAMMATION 21 97.48 Very High Very High Very High
Hyperalgesia 9 89.76 High High
Pain 21 82.12 Quite High
Pressure And Volume Under Development 3 76.72 Quite High
Nociception 9 22.44 Low Low
Inflammatory Pain 13 5.00 Very Low Very Low Very Low
Neuropathic Pain 4 5.00 Very Low Very Low Very Low
Myelodysplastic Syndromes 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, we found Hyp significantly reversed the up-regulated NR2B receptors in the PAG from mice with peripheral injury, whereas it did not affect the NR2B receptor expression in the normal physiological conditions.
Hyp Neg (not) Regulation (affect) of Gene_expression (expression) of NR2B associated with injury and central grey
1) Confidence 0.08 Published 2009 Journal Mol Pain Section Body Doc Link PMC2803476 Disease Relevance 1.39 Pain Relevance 1.04

General Comments

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