INT292052

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.47
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 2.50
Pain Relevance 1.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell morphogenesis (Csnk1a1) cytoplasm (Csnk1a1) mitosis (Csnk1a1)
chromosome (Csnk1a1) nucleus (Csnk1a1) cytoskeleton (Csnk1a1)
Anatomy Link Frequency
spinal nerve 2
Csnk1a1 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 136 99.28 Very High Very High Very High
dorsal root ganglion 128 98.00 Very High Very High Very High
Peripheral nervous system 4 92.64 High High
Neuropathic pain 148 88.56 High High
spinal dorsal horn 32 82.72 Quite High
glial activation 8 81.68 Quite High
Dorsal horn 68 81.20 Quite High
nMDA receptor 12 79.20 Quite High
Glutamate receptor 32 78.08 Quite High
Glutamate 16 65.68 Quite High
Disease Link Frequency Relevance Heat
Nervous System Injury 64 99.88 Very High Very High Very High
Injury 112 99.68 Very High Very High Very High
Ganglion Cysts 128 98.00 Very High Very High Very High
Neuropathic Pain 196 88.56 High High
Apoptosis 8 81.92 Quite High
Spinal Injuries 4 64.28 Quite High
Congenital Anomalies 8 37.88 Quite Low
Pain 28 36.92 Quite Low
Hyperalgesia 24 34.24 Quite Low
Nociception 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
From this preliminary comparative cDNA microarray analysis, we found that the spinal nerve injury down-regulated the expression of casein kinase 1 epsilon (CK1?)
Regulation (regulated) of Gene_expression (expression) of CK1 in spinal nerve associated with nervous system injury
1) Confidence 0.47 Published 2009 Journal Mol Pain Section Body Doc Link PMC2804670 Disease Relevance 0.91 Pain Relevance 0.58
To our knowledge, this is the first report demonstrating the alteration of the expression pattern of CK1?
Regulation (alteration) of Gene_expression (expression) of CK1
2) Confidence 0.47 Published 2009 Journal Mol Pain Section Body Doc Link PMC2804670 Disease Relevance 0.59 Pain Relevance 0.57
If the SNL injury down regulates some of the gene expression including CK1?
Regulation (some) of Gene_expression (expression) of CK1 associated with injury
3) Confidence 0.34 Published 2009 Journal Mol Pain Section Body Doc Link PMC2804670 Disease Relevance 0.50 Pain Relevance 0.34
Thus further rigorous study would be necessary to clarify the role of N-type Ca2+ channel on the expression of CK1?.
Regulation (role) of Gene_expression (expression) of CK1
4) Confidence 0.20 Published 2009 Journal Mol Pain Section Body Doc Link PMC2804670 Disease Relevance 0.50 Pain Relevance 0.14

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox