INT292137

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.75
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Mtor, VEGFA) mitochondrion (Mtor) Golgi apparatus (Mtor)
endoplasmic reticulum (Mtor) cytosol (Mtor) extracellular space (VEGFA)
Mtor (Mus musculus)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 6 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
positron emission tomography 3 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 75 99.84 Very High Very High Very High
Ovarian Cancer 100 97.28 Very High Very High Very High
Colon Cancer 1 62.88 Quite High
Hypertension 4 58.16 Quite High
Proteinuria 1 54.64 Quite High
Hemorrhage 2 51.28 Quite High
Injury 1 48.08 Quite Low
Embolism 1 42.08 Quite Low
Disease 9 5.00 Very Low Very Low Very Low
Solid Tumor 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since the mammalian target of rapamycin (mTOR) pathway regulates VEGF expression in cancer cells [32], researchers combined BEV and rapamycin in an ovarian cancer xenograft model and found a 94% reduction in tumor growth as well as a prolonged survival [33].
Regulation (target) of mTOR Regulation (regulates) of Gene_expression (expression) of VEGF associated with cancer and ovarian cancer
1) Confidence 0.01 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC2804796 Disease Relevance 0.75 Pain Relevance 0

General Comments

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