INT292294

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.66
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Myh1, HIVEP1) nucleus (HIVEP1) intracellular (HIVEP1)
DNA binding (HIVEP1)
Anatomy Link Frequency
myeloid progenitor cells 3
monocytes 1
Myh1 (Mus musculus)
HIVEP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 4 21.32 Low Low
cytokine 24 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Migraine 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 282 100.00 Very High Very High Very High
Disease 18 94.88 High High
Immunodeficiency 8 58.20 Quite High
Infection 22 5.00 Very Low Very Low Very Low
Cancer 20 5.00 Very Low Very Low Very Low
Dementia 18 5.00 Very Low Very Low Very Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low
Necrosis 6 5.00 Very Low Very Low Very Low
Disease Progression 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Unstimulated peripheral monocytes and myeloid progenitor cells support low levels of viral replication and transcription in response to cellular activation [27,36,48-54], whereas differentiated MDMs have increased viral replication but either do not respond to [45] or downregulate HIV transcription [48,55] in response to cellular stimulation.
MDMs Neg (not) Negative_regulation (downregulate) of Transcription (transcription) of HIV in myeloid progenitor cells associated with acquired immune deficiency syndrome or hiv infection
1) Confidence 0.00 Published 2009 Journal Retrovirology Section Body Doc Link PMC2805609 Disease Relevance 0.83 Pain Relevance 0
Unstimulated peripheral monocytes and myeloid progenitor cells support low levels of viral replication and transcription in response to cellular activation [27,36,48-54], whereas differentiated MDMs have increased viral replication but either do not respond to [45] or downregulate HIV transcription [48,55] in response to cellular stimulation.
MDMs Neg (not) Negative_regulation (downregulate) of in monocytes Transcription (transcription) of HIV in myeloid progenitor cells associated with acquired immune deficiency syndrome or hiv infection
2) Confidence 0.00 Published 2009 Journal Retrovirology Section Body Doc Link PMC2805609 Disease Relevance 0.83 Pain Relevance 0

General Comments

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