INT292304

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Context Info
Confidence 0.69
First Reported 2009
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 12
Disease Relevance 0.26
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (PLXNB1) extracellular region (PLXNB1) plasma membrane (PLXNB1)
intracellular (PLXNB1)
Anatomy Link Frequency
fallopian tube 3
endometrium 3
ovary 2
PLXNB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 36 82.60 Quite High
pain pelvic 12 46.40 Quite Low
endometriosis 12 35.52 Quite Low
cytokine 12 35.32 Quite Low
Inflammation 24 34.32 Quite Low
Disease Link Frequency Relevance Heat
Malignant Neoplastic Disease 24 75.76 Quite High
Disease 12 73.68 Quite High
Breast Cancer 12 54.72 Quite High
Reprotox - General 1 12 51.76 Quite High
Uterine Prolapse 12 49.60 Quite Low
Reprotox - General 3 24 46.40 Quite Low
Adhesions 12 39.68 Quite Low
Endometriosis (extended) 12 35.52 Quite Low
INFLAMMATION 24 34.32 Quite Low
Communicable Diseases 12 33.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Plexin B1 expression during the menstrual cycle, in the human endometrium and in the fallopian tube
Gene_expression (expression) of Plexin B1 in endometrium
1) Confidence 0.69 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2805671 Disease Relevance 0 Pain Relevance 0
To the best of our knowledge, this is the first report showing the expression of Plexin B1 in human endometrial tissue.
Gene_expression (expression) of Plexin B1
2) Confidence 0.69 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2805671 Disease Relevance 0 Pain Relevance 0
Plexin B1 expression was found in the mouse ovary, suggesting a possible role for the receptor in follicular growth and development [16].
Gene_expression (expression) of Plexin B1 in ovary
3) Confidence 0.69 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2805671 Disease Relevance 0 Pain Relevance 0
In the present study plexin B1 expression was found in human endometrial tissue and its level was found to be significantly higher at the period corresponding with the implantation window.
Gene_expression (expression) of plexin B1
4) Confidence 0.60 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2805671 Disease Relevance 0.05 Pain Relevance 0.06
Plexin-B1, glycodelin and MMP7 expression in the human fallopian tube and in the endometrium

Background

Gene_expression (expression) of Plexin-B1 in fallopian tube
5) Confidence 0.54 Published 2009 Journal Reprod Biol Endocrinol Section Title Doc Link PMC2805671 Disease Relevance 0 Pain Relevance 0
To compare Plexin B1 mRNA relative expression levels between periods, we analyzed the ratio of each independent experiment between the expression level of either Plexin B1 and GAPDH from the same tissue.
Gene_expression (expression) of Plexin B1
6) Confidence 0.54 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2805671 Disease Relevance 0 Pain Relevance 0
A total of 22 endometrial and fallopian tube biopsies were analyzed for plexin B1 expression (Table 2, Figure 3).
Spec (analyzed) Gene_expression (expression) of plexin B1 in fallopian tube
7) Confidence 0.54 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2805671 Disease Relevance 0 Pain Relevance 0
Plexin B1 expression in the endometrium during days 19 - 23 was significantly higher compared to days 12 - 14 (1.166 ± 0.42 versus 0.523 ± 0.299, P < 0.005).
Gene_expression (expression) of Plexin B1 in endometrium
8) Confidence 0.54 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2805671 Disease Relevance 0 Pain Relevance 0
Recently, Plexin B1 was found to be expressed in the mouse ovary and to have a role in follicular growth and steroidogenesis [16] and in endometrial receptivity of human endometrial cell lines [17].


Gene_expression (expressed) of Plexin B1 in ovary
9) Confidence 0.54 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2805671 Disease Relevance 0.20 Pain Relevance 0.04
To study the expression of Plexin-B1, Glycodelin, and MMP7 during the menstrual cycle in the endometrium and in the fallopian tube.


Gene_expression (expression) of Plexin-B1 in fallopian tube
10) Confidence 0.54 Published 2009 Journal Reprod Biol Endocrinol Section Abstract Doc Link PMC2805671 Disease Relevance 0 Pain Relevance 0
Plexin-B1 expression in the endometrium was significantly higher on days 19 - 23 compared to days 12 - 14 (1.166 +/- 0.42 versus 0.523 +/- 0.299), P < 0.005.
Gene_expression (expression) of Plexin-B1 in endometrium
11) Confidence 0.54 Published 2009 Journal Reprod Biol Endocrinol Section Abstract Doc Link PMC2805671 Disease Relevance 0 Pain Relevance 0
Figure 3 summarizes Plexin B1 expression through various periods during the menstrual cycle.
Gene_expression (expression) of Plexin B1
12) Confidence 0.54 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2805671 Disease Relevance 0 Pain Relevance 0

General Comments

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