INT29231

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Context Info
Confidence 0.53
First Reported 1985
Last Reported 2010
Negated 5
Speculated 0
Reported most in Body
Documents 44
Total Number 44
Disease Relevance 10.08
Pain Relevance 4.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Dbp)
Anatomy Link Frequency
heart 4
blood 2
tooth 1
midbrain 1
Dbp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Opioid 12 100.00 Very High Very High Very High
qutenza 4 100.00 Very High Very High Very High
Morphine 5 99.46 Very High Very High Very High
opioid receptor 4 99.20 Very High Very High Very High
Inflammation 56 99.16 Very High Very High Very High
Dopamine 40 98.90 Very High Very High Very High
Mcgill questionnaire 1 98.68 Very High Very High Very High
midbrain 6 98.64 Very High Very High Very High
Potency 4 97.84 Very High Very High Very High
Clonidine 3 97.84 Very High Very High Very High
Disease Link Frequency Relevance Heat
Bradycardia 18 100.00 Very High Very High Very High
Myocardial Infarction 27 99.46 Very High Very High Very High
INFLAMMATION 57 99.16 Very High Very High Very High
Hypertension 701 98.64 Very High Very High Very High
Pain 39 98.12 Very High Very High Very High
Heart Failure 3 97.64 Very High Very High Very High
Hypotension 14 95.88 Very High Very High Very High
Stroke 49 94.00 High High
Drug Induced Neurotoxicity 1 90.76 High High
Spinal Cord Injury 62 90.24 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There was no change in SBP, DBP and LVP.
Neg (no) Regulation (change) of DBP
1) Confidence 0.53 Published 1985 Journal Nippon Yakurigaku Zasshi Section Abstract Doc Link 4029805 Disease Relevance 0.31 Pain Relevance 0.15
Effect of DBP/DEHP in vegetable planted soil on the quality of capsicum fruit.
Regulation (Effect) of DBP associated with qutenza
2) Confidence 0.39 Published 2003 Journal Chemosphere Section Title Doc Link 12688494 Disease Relevance 0 Pain Relevance 0.23
Furthermore, chronic administration of morphine results in a selective up-regulation of the mu binding site.
Regulation (regulation) of mu binding site associated with morphine
3) Confidence 0.27 Published 1987 Journal Eur. J. Pharmacol. Section Abstract Doc Link 2826178 Disease Relevance 0 Pain Relevance 0.76
Endralazine was started at a dose of 10 mg o.d. and increased by 10 mg to a maximum of 40 mg o.d. until seated DBP was controlled below 95 mmHg.
Regulation (controlled) of DBP
4) Confidence 0.27 Published 1986 Journal Eur. J. Clin. Pharmacol. Section Abstract Doc Link 3758143 Disease Relevance 0.46 Pain Relevance 0.11
Changes in SBP and DBP during the study period in the overall population as well as in the different cardiovascular risk groups are shown in Table 4.
Regulation (Changes) of DBP
5) Confidence 0.25 Published 2006 Journal International Journal of Clinical Practice Section Body Doc Link PMC1636683 Disease Relevance 0.43 Pain Relevance 0
Secondary efficacy variables included mean changes in DBP, systolic blood pressure (SBP), and response rate (defined as the proportion of patients whose DBP was <90 mm Hg or whose DBP had decreased from baseline by > or =10 mm Hg).
Regulation (changes) of DBP in blood
6) Confidence 0.23 Published 2005 Journal Clin Ther Section Body Doc Link 16117979 Disease Relevance 0 Pain Relevance 0
The mean change in 24-h SBP, DBP, heart rate, urinary Na+, K+, protein and creatinine, creatinine clearance and serum electrolytes were compared across treatments in the total cohort and in ISH and control groups separately using ANCOVA (SAS).
Regulation (change) of DBP in heart
7) Confidence 0.19 Published 1999 Journal J. Hypertens. Section Body Doc Link 10466476 Disease Relevance 0 Pain Relevance 0
At the final visit, DBP control was achieved in 70.0% (194/277) of patients in the telmisartan monotherapy group and by 56%, 55%, and 65% of the patients receiving telmisartan/hydrochlorothiazide 80/12.5 mg/day, 80/25 mg/day, or telmisartan 80 mg plus another antihypertensive with or without the hydrochlorothiazide (12.5 or 25 mg).
Regulation (control) of DBP
8) Confidence 0.15 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2293961 Disease Relevance 0.06 Pain Relevance 0
In the case of BP, no significant changes were recorded; the highest mean SBP and DBP values were observed at the time of ostectomy and/or tooth sectioning.
Regulation (values) of DBP in tooth
9) Confidence 0.14 Published 2008 Journal J. Oral Maxillofac. Surg. Section Body Doc Link 18280377 Disease Relevance 0 Pain Relevance 0
The highest and lowest values of SBP and DBP achieved during the sets and the rest periods in each exercise protocol are shown for each cohort in Figure 2.
Regulation (values) of DBP
10) Confidence 0.14 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2845767 Disease Relevance 0.26 Pain Relevance 0
Landiolol reduces HR rapidly and in a dose-dependent manner whereas landiolol-induced changes in sBP and dBP are independent of dose.
Regulation (changes) of dBP
11) Confidence 0.14 Published 2007 Journal Eur. J. Clin. Pharmacol. Section Body Doc Link 17211618 Disease Relevance 0 Pain Relevance 0
Landiolol causes a rapid and dose-dependent decrease in HR, whereas landiolol-induced changes in sBP and dBP are independent of dose.
Regulation (changes) of dBP
12) Confidence 0.14 Published 2007 Journal Eur. J. Clin. Pharmacol. Section Body Doc Link 17211618 Disease Relevance 0 Pain Relevance 0
At the end of the randomized treatment phase, patients who had received olmesartan 20 mg/HCTZ 12.5 mg showed larger a change in SBP and DBP (?
Regulation (change) of DBP
13) Confidence 0.13 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2663442 Disease Relevance 0.14 Pain Relevance 0
After adjusting for myocardial infarction, a one-standard deviation change in SBP, DBP, and pulse pressure was associated with hazard ratios (95% confidence intervals) of 1.24 (1.15-1.35), 1.13 (1.04-1.22), and 1.21 (1.12-1.31), respectively.
Regulation (change) of DBP associated with myocardial infarction
14) Confidence 0.13 Published 2008 Journal Current Cardiology Reviews Section Body Doc Link PMC2774582 Disease Relevance 1.40 Pain Relevance 0.03
In the treatment of stage II hypertensive patient the FDC of T40+A5 (Telar-AM) was found to be significantly effective in the reduction of SBP as well as DBP.
Regulation (effective) of DBP associated with hypertension
15) Confidence 0.12 Published 2008 Journal J Indian Med Assoc Section Abstract Doc Link 19552093 Disease Relevance 0.87 Pain Relevance 0.09
In animals which exhibited an incomplete loss of dopamine uptake sites (less than 80%) there was no significant change in opioid binding site density.
Neg (no) Regulation (change) of opioid binding site associated with dopamine and opioid
16) Confidence 0.12 Published 1993 Journal Neuroscience Section Abstract Doc Link 8232904 Disease Relevance 0 Pain Relevance 0.73
10 mmHg from baseline); the proportion of patients achieving a target sitting DBP of ?
Regulation (sitting) of DBP
17) Confidence 0.12 Published 2006 Journal Vascular Health and Risk Management Section Body Doc Link PMC1994016 Disease Relevance 0.07 Pain Relevance 0
All the values of PWV, SBP, DBP, and heart rate increased after discontinuation of anesthesia.
Regulation (values) of DBP in heart
18) Confidence 0.11 Published 2006 Journal Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists Section Body Doc Link 17233362 Disease Relevance 0 Pain Relevance 0
Just after tracheal intubation, dBP in all groups was unchanged, and dBP in the Groups C and L 4 decreased from the baseline 10 min after the intubation.
Neg (unchanged) Regulation (unchanged) of dBP
19) Confidence 0.10 Published 2006 Journal Masui Section Body Doc Link 16491894 Disease Relevance 0 Pain Relevance 0
SBP and DBP peak and trough values for daytime and nighttime were entered independently in the analysis.
Regulation (values) of DBP
20) Confidence 0.10 Published 2009 Journal Korean Journal of Ophthalmology : KJO Section Body Doc Link PMC2655738 Disease Relevance 0 Pain Relevance 0.05

General Comments

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