INT292334

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 0.07
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Fig4) mitochondrion (Sds) lyase activity (Sds)
Golgi apparatus (Fig4) endoplasmic reticulum (Fig4) cellular_component (Sds)
Anatomy Link Frequency
joints 1
Sds (Rattus norvegicus)
Fig4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
imagery 5 91.08 High High
ketamine 5 5.00 Very Low Very Low Very Low
anesthesia 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 5 73.28 Quite High
Alzheimer's Dementia 35 38.44 Quite Low
Adult Respiratory Distress Syndrome 45 31.92 Quite Low
Infant Respiratory Distress Syndrome 10 23.12 Low Low
Respiratory Distress 5 22.88 Low Low
Infection 5 13.88 Low Low
Interstitial Lung Diseases 5 12.24 Low Low
Pulmonary Alveolar Proteinosis 15 5.00 Very Low Very Low Very Low
Primary Sclerosing Cholangitis 5 5.00 Very Low Very Low Very Low
Body Weight 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the other hand, aqueous dimeric saposin B [19] or saposin C bound to submicellar SDS detergent [20] (Fig. 1A, B) show opened conformations, in which the leaves of the V are now far apart having expanded at the flexible joints.
SDS Binding (bound) of Fig in joints
1) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2805716 Disease Relevance 0 Pain Relevance 0
These SPR results indicating much higher self-association for S-MB than that noted for MB are supportive of our SDS-PAGE findings indicating dimer formation for S-MB but not for MB (Fig. 8).


SDS Binding (formation) of Fig
2) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2805716 Disease Relevance 0 Pain Relevance 0
Because both saposin C (Fig. 1) [20] and the “10 nsec” dimer S-MB model (Figs. 11B and 12) share an open, ‘saposin-like’ conformation when bound to submicellar SDS, it is tempting to speculate that dimer S-MB may exert its surfactant activities by analogously binding to lipid bilayers and monolayers.
SDS Binding (bound) of Fig
3) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2805716 Disease Relevance 0 Pain Relevance 0.05
These SPR results indicating much higher self-association for S-MB than that noted for MB are supportive of our SDS-PAGE findings indicating dimer formation for S-MB but not for MB (Fig. 8).


SDS Binding (formation) of Fig
4) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2805716 Disease Relevance 0 Pain Relevance 0
In the “0 nsec” dimer S-MB structure of Fig. 11A, anionic SDS closely associates not only with exposed nonpolar residues through hydrophobic interactions, but also with positively-charged Arg and Lys residues through electrostatic interactions.
SDS Binding (associates) of Fig
5) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2805716 Disease Relevance 0.07 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox