INT292401

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.76
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (VEGFA, fgf1a) extracellular region (VEGFA, fgf1a) cytoplasm (VEGFA, fgf1a)
cell differentiation (fgf1a) growth (VEGFA) proteinaceous extracellular matrix (VEGFA)
Anatomy Mention Frequency
VBM 1
VEGFA (Homo sapiens)
fgf1a (Danio rerio)
Pain Term Frequency Confidence Heat
rheumatoid arthritis 1 90.36 High High
cINOD 1 5.00 Very Low Very Low Very Low
Disease Term Frequency Confidence Heat
Cancer 12 93.80 High High
Diabetic Retinopathy 1 91.36 High High
Rheumatoid Arthritis 1 90.36 High High
Wound Healing 1 87.16 High High
Solid Tumor 1 74.96 Quite High
Toxicity 1 18.32 Low Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Breast Cancer 1 5.00 Very Low Very Low Very Low
Adverse Drug Reaction 1 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Angiogenesis involves the coordination of several steps: (i) binding of angiogenic stimulating factors [vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF)] to their receptors on endothelial cells, (ii) secretion of proteases, which degrade the vascular basement membrane (VBM) and the surrounding ECM, (iii) endothelial proliferation and migration, (iv) endothelial differentiation and tube formation, (v) reformation of the VBM, (vi) recruitment of pericytes, which surround and stabilize the newly formed vessel (4–6).


vascular endothelial growth factor Binding (binding) of fibroblast growth factor in VBM
1) Confidence 0.01 Published 2010 Journal Apmis Section Body Doc Link PMC2806050 Disease Relevance 0.76 Pain Relevance 0.05

General Comments

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