INT29241

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Context Info
Confidence 0.09
First Reported 1988
Last Reported 1988
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.22

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cytoplasm (OPRD1, POMC) small molecule metabolic process (POMC) cell-cell signaling (POMC)
signal transducer activity (OPRD1) extracellular space (POMC) generation of precursor metabolites and energy (POMC)
OPRD1 (Homo sapiens)
POMC (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 4 100.00 Very High Very High Very High
Enkephalin 1 84.64 Quite High
Delta opioid receptors 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IC50 values for binding to mu and delta opioid receptor sites were 3-8 times higher for monobiotinylated derivatives than for the parent human beta-endorphin (IC50,mu = 1.5 nM, IC50,delta = 1.3 nM).
delta opioid receptor Binding (binding) of beta-endorphin associated with opioid receptor
1) Confidence 0.09 Published 1988 Journal J. Biol. Chem. Section Abstract Doc Link 2826453 Disease Relevance 0 Pain Relevance 0.22

General Comments

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