INT292492

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Context Info
Confidence 0.04
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.11
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear chromosome (Birc5) chromosome segregation (Birc5) intracellular (Birc5)
enzyme binding (Birc5) embryo development (Birc5) cytoplasm (Birc5)
Anatomy Link Frequency
AsPC-1 4
Mlph (Mus musculus)
Birc5 (Mus musculus)
Pain Link Frequency Relevance Heat
palliative 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 74 95.08 Very High Very High Very High
Pancreatic Cancer 96 81.60 Quite High
Cancer 34 60.00 Quite High
Adhesions 14 10.76 Low Low
Metastasis 8 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 4 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Breast Cancer 2 5.00 Very Low Very Low Very Low
Lung Cancer 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, inhibition of FAK phosphorylation by FRNK overexpression antagonized the effects of LN on survivin expression and Bad phosphorylation at Ser136 in AsPC-1 cells (Fig. 10D).
LN Regulation (effects) of Gene_expression (expression) of survivin in AsPC-1
1) Confidence 0.04 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2806309 Disease Relevance 0.45 Pain Relevance 0
Consistent with the results of FAK RNAi and FRNK overexpression, PF-228 decreased survivin expression and Bad phosphorylation at Ser136 in Panc-1 cells and antagonized the effects of LN on survivin expression and Bad phosphorylation at Ser136 in AsPC-1 cells (Fig. 14A-B).
LN Regulation (effects) of Gene_expression (expression) of survivin in AsPC-1
2) Confidence 0.03 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2806309 Disease Relevance 0.65 Pain Relevance 0

General Comments

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