INT292494

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.84
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (AKT1) nucleoplasm (AKT1) transport (AKT1)
small molecule metabolic process (AKT1) enzyme binding (AKT1) carbohydrate metabolic process (AKT1)
Anatomy Link Frequency
AsPC-1 6
Mlph (Mus musculus)
AKT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 144 95.76 Very High Very High Very High
Apoptosis 111 93.84 High High
Adhesions 21 72.56 Quite High
Death 3 28.92 Quite Low
Cancer 51 5.00 Very Low Very Low Very Low
Metastasis 12 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 6 5.00 Very Low Very Low Very Low
Breast Cancer 3 5.00 Very Low Very Low Very Low
Lung Cancer 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results indicated that in AsPC-1 cells, LN induced FAK and Akt phosphorylation in a time-dependent manner, and LN-induced Akt phosphorylation was mediated by FAK activation.


LN Positive_regulation (induced) of Phosphorylation (phosphorylation) of Akt in AsPC-1
1) Confidence 0.01 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2806309 Disease Relevance 0.22 Pain Relevance 0
LN induces the phosphorylation of FAK and its downstream kinase Akt in AsPC-1 cells
LN Positive_regulation (induces) of Phosphorylation (phosphorylation) of Akt in AsPC-1
2) Confidence 0.01 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2806309 Disease Relevance 0.40 Pain Relevance 0
These results indicated that in AsPC-1 cells, LN induced FAK and Akt phosphorylation in a time-dependent manner, and LN-induced Akt phosphorylation was mediated by FAK activation.


LN Positive_regulation (induced) of Phosphorylation (phosphorylation) of Akt in AsPC-1
3) Confidence 0.01 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2806309 Disease Relevance 0.23 Pain Relevance 0

General Comments

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