INT292531

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Context Info
Confidence 0.15
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.13
Pain Relevance 1.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Mapk14) cell morphogenesis (Mapk14) intracellular (Il10)
response to stress (Mapk14) cytoplasm (Mapk14) cytosol (Mapk14)
Anatomy Link Frequency
immune cells 2
Il10 (Rattus norvegicus)
Mapk14 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Antihyperalgesic 1 99.12 Very High Very High Very High
Hyperalgesia 77 94.04 High High
Inflammation 62 93.36 High High
cytokine 26 85.64 High High
Pain 12 74.16 Quite High
Lasting pain 9 71.32 Quite High
allodynia 8 43.24 Quite Low
Neuropathic pain 4 38.16 Quite Low
nMDA receptor antagonist 2 35.04 Quite Low
nMDA receptor 9 23.28 Low Low
Disease Link Frequency Relevance Heat
Hyperalgesia 77 94.04 High High
INFLAMMATION 68 93.36 High High
Pain 21 74.16 Quite High
Injury 12 70.00 Quite High
Neuropathic Pain 12 43.24 Quite Low
Nervous System Injury 5 42.52 Quite Low
Mucocutaneous Lymph Node Syndrome 1 24.44 Low Low
Nociception 5 8.24 Low Low
Necrosis 2 5.00 Very Low Very Low Very Low
Dermatitis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Importantly, IL-10 suppresses p38 mitogen-activated protein kinase activation in immune cells [81], which may be a key interface between IL-10 and glial cells in producing antihyperalgesia [see [56]].
IL-10 Negative_regulation (suppresses) of Positive_regulation (activation) of p38 in immune cells
1) Confidence 0.15 Published 2009 Journal Mol Pain Section Body Doc Link PMC2806354 Disease Relevance 1.13 Pain Relevance 1.06

General Comments

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