INT292571

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.80
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL6) aging (IL6) extracellular region (IL6)
Golgi apparatus (F2RL1) plasma membrane (F2RL1) signal transducer activity (F2RL1)
F2RL1 (Homo sapiens)
IL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory mediators 1 100.00 Very High Very High Very High
Inflammatory response 1 95.68 Very High Very High Very High
cytokine 4 83.36 Quite High
Inflammation 10 75.52 Quite High
IPN 1 48.76 Quite Low
Arthritis 1 48.00 Quite Low
agonist 13 5.00 Very Low Very Low Very Low
antagonist 5 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 12 100.00 Very High Very High Very High
Stress 2 89.48 High High
Reperfusion Injury 1 60.80 Quite High
Cv Unclassified Under Development 1 60.04 Quite High
Contact Dermatitis 1 51.96 Quite High
Colitis 1 49.24 Quite Low
Inflammatory Pain 1 48.76 Quite Low
Arthritis 1 48.00 Quite Low
Disease 2 46.60 Quite Low
Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previous studies have demonstrated that activation of PAR2 leads to the release of several potent pro-inflammatory mediators, including IL-6, IL-8, TNF?
Positive_regulation (activation) of PAR2 Positive_regulation (leads) of Localization (release) of IL-6 associated with inflammatory mediators
1) Confidence 0.07 Published 2010 Journal Cellular Signalling Section Body Doc Link PMC2806525 Disease Relevance 0.80 Pain Relevance 0.27

General Comments

This test has worked.

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