INT29258

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Context Info
Confidence 0.42
First Reported 1988
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.16
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ifnb1) extracellular region (Ifnb1)
Anatomy Link Frequency
Poly 2
Ifnb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Multiple sclerosis 86 99.92 Very High Very High Very High
addiction 1 75.00 Quite High
Inflammation 4 71.88 Quite High
Central nervous system 10 47.08 Quite Low
imagery 14 41.28 Quite Low
nociceptor 1 25.00 Low Low
adenocard 4 5.00 Very Low Very Low Very Low
Dermatone 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Demyelinating Disease 90 99.92 Very High Very High Very High
Nociception 3 99.28 Very High Very High Very High
Muscular Dystrophy 6 98.16 Very High Very High Very High
Disease 26 97.32 Very High Very High Very High
INFLAMMATION 4 71.88 Quite High
Central Nervous System Disease 10 47.08 Quite Low
Recurrence 24 5.00 Very Low Very Low Very Low
Infection 12 5.00 Very Low Very Low Very Low
Progressive Multifocal Leukoencephalopathy 10 5.00 Very Low Very Low Very Low
Reprotox - General 1 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results show that the observed conditioned enhancement of NK activity in conditioned animals is not caused by any nociceptive properties of the CS itself and is dependent on the IFN-beta produced after Poly I:C injection in the conditioned paradigm.
Neg (not) Positive_regulation (dependent) of Gene_expression (produced) of IFN-beta in Poly associated with nociception
1) Confidence 0.42 Published 1988 Journal J. Immunol. Section Abstract Doc Link 2826599 Disease Relevance 0.17 Pain Relevance 0.04
Ever since, interferon beta (IFN?)
Positive_regulation (Ever) of Gene_expression (Ever) of interferon beta
2) Confidence 0.05 Published 2010 Journal Drug Des Devel Ther Section Body Doc Link PMC2915536 Disease Relevance 0.99 Pain Relevance 0.24
Ever since, interferon beta (IFN?)
Positive_regulation (since) of Gene_expression (Ever) of interferon beta
3) Confidence 0.05 Published 2010 Journal Drug Des Devel Ther Section Body Doc Link PMC2915536 Disease Relevance 0.99 Pain Relevance 0.24

General Comments

This test has worked.

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