INT292587

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Context Info
Confidence 0.23
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.45
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MAPK8) nucleoplasm (MAPK8) mitochondrion (MAPK8)
nucleus (MAPK8) response to stress (MAPK8) cytoplasm (MAPK8)
MAPK8 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 13 46.76 Quite Low
antagonist 5 34.44 Quite Low
Inflammation 41 5.00 Very Low Very Low Very Low
cytokine 12 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 92 99.40 Very High Very High Very High
Myeloid Leukemia 29 98.32 Very High Very High Very High
INFLAMMATION 50 5.00 Very Low Very Low Very Low
Periodontitis 17 5.00 Very Low Very Low Very Low
Diabetes Mellitus 13 5.00 Very Low Very Low Very Low
Disease 11 5.00 Very Low Very Low Very Low
Diabetic Retinopathy 10 5.00 Very Low Very Low Very Low
Cancer 5 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low
Periodontal Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
have not revealed a specific isoform to date responsible for JNK inhibition (not shown).
Regulation (responsible) of Negative_regulation (inhibition) of JNK
1) Confidence 0.23 Published 2010 Journal Cellular Signalling Section Body Doc Link PMC2806525 Disease Relevance 0 Pain Relevance 0
For this purpose, we investigated the effect of specific inhibitors of the JNK and NF-?
Spec (investigated) Regulation (effect) of Spec (investigated) Negative_regulation (inhibitors) of JNK
2) Confidence 0.17 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2873473 Disease Relevance 0 Pain Relevance 0
Doubling the concentration of p38 and JNK inhibitors did not significantly increase their inhibitory effect on TNF-?
Regulation (concentration) of Negative_regulation (inhibitors) of JNK
3) Confidence 0.09 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2838737 Disease Relevance 1.45 Pain Relevance 0

General Comments

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