INT292591

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Context Info
Confidence 0.35
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (F2RL1) plasma membrane (F2RL1) signal transducer activity (F2RL1)
F2RL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 15 96.96 Very High Very High Very High
agonist 39 90.16 High High
cytokine 12 45.36 Quite Low
Inflammation 30 42.64 Quite Low
chemokine 3 19.64 Low Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
IPN 3 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 36 42.64 Quite Low
Cancer 6 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Stress 6 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 3 5.00 Very Low Very Low Very Low
Reperfusion Injury 3 5.00 Very Low Very Low Very Low
Inflammatory Pain 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study we demonstrated complete reversal of PAR2 mediated JNK inhibition.
Negative_regulation (reversal) of Negative_regulation (inhibition) of PAR2
1) Confidence 0.35 Published 2010 Journal Cellular Signalling Section Body Doc Link PMC2806525 Disease Relevance 0 Pain Relevance 0
Whilst in this present study we show that K-14585 is able to reverse PAR2 mediated inhibition of TNF?
Negative_regulation (reverse) of Negative_regulation (inhibition) of PAR2
2) Confidence 0.35 Published 2010 Journal Cellular Signalling Section Body Doc Link PMC2806525 Disease Relevance 0 Pain Relevance 0.36
Both agents effectively reversed PAR2 mediated disruption of TNF?
Negative_regulation (reversed) of Negative_regulation (disruption) of PAR2
3) Confidence 0.35 Published 2010 Journal Cellular Signalling Section Body Doc Link PMC2806525 Disease Relevance 0 Pain Relevance 0

General Comments

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