INT292608

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.58
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (GABRB3) transport (GABRB3) plasma membrane (GABRB3)
transmembrane transport (GABRB3)
GABRB3 (Homo sapiens)
Pain Link Frequency Relevance Heat
nMDA receptor 1 99.80 Very High Very High Very High
cannabis 52 98.76 Very High Very High Very High
drug abuse 6 94.88 High High
Transcranial magnetic stimulation 36 90.84 High High
GABAergic 18 5.00 Very Low Very Low Very Low
Cannabinoid 9 5.00 Very Low Very Low Very Low
alcohol 6 5.00 Very Low Very Low Very Low
gABA 6 5.00 Very Low Very Low Very Low
Delta-9-tetrahydrocannabinol 4 5.00 Very Low Very Low Very Low
addiction 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Schizophrenia 106 97.56 Very High Very High Very High
Drug Dependence 43 94.88 High High
Cannabis Dependence 24 93.64 High High
Disease 7 88.64 High High
Syndrome 3 88.00 High High
Congenital Anomalies 3 49.64 Quite Low
Handedness 2 5.00 Very Low Very Low Very Low
Dementia 2 5.00 Very Low Very Low Very Low
Psychosis 2 5.00 Very Low Very Low Very Low
Severe Combined Immunodeficiency 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This finding suggests an increased alteration of GABAA and NMDA receptor activity in cannabis-abusing first-episode patients as compared to schizophrenia patients with no history of substance abuse.
Positive_regulation (increased) of Regulation (alteration) of GABAA associated with cannabis, drug abuse, nmda receptor and schizophrenia
1) Confidence 0.05 Published 2009 Journal Psychopharmacology (Berl) Section Abstract Doc Link PMC2806533 Disease Relevance 1.58 Pain Relevance 0.45

General Comments

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