INT292621

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 3.88
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL6) aging (IL6) extracellular region (IL6)
biosynthetic process (Gpt) cytoplasm (Gpt)
Anatomy Link Frequency
liver 1
IL6 (Homo sapiens)
Gpt (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 64 96.28 Very High Very High Very High
Inflammation 8 80.48 Quite High
abdominal pain 12 12.00 Low Low
cva 6 5.28 Low Low
Pain 10 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Dengue Hemorrhagic Fever 182 100.00 Very High Very High Very High
Thrombocytopenia 24 100.00 Very High Very High Very High
Pressure And Volume Under Development 10 100.00 Very High Very High Very High
Pleural Effusion 10 100.00 Very High Very High Very High
Hepatotoxicity 2 99.36 Very High Very High Very High
Dengue 166 96.84 Very High Very High Very High
Disease 22 88.92 High High
Infection 42 84.92 Quite High
INFLAMMATION 12 80.48 Quite High
Sprains And Strains 2 18.08 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
, IL-6 and IL-8 with parameters indicative of cell damage, thrombocytopenia, a correlate of platelet destruction, increased hematocrit values, pleural effusion/ascites, indicative of endothelial cell dysfunction and raised AST/ALT, suggestive of liver damage.
IL-6 Binding (raised) of ALT in liver associated with pleural effusion, pressure and volume under development, hepatotoxicity and thrombocytopenia
1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2806829 Disease Relevance 1.80 Pain Relevance 0.16
IL-6 was also associated with presence of pleural effusion/ascites in DHF, consistent with an earlier report [19] but not with thrombocytopenia or increased ALT.
IL-6 Binding (associated) of ALT associated with pleural effusion, pressure and volume under development, thrombocytopenia and dengue hemorrhagic fever
2) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2806829 Disease Relevance 2.08 Pain Relevance 0.08

General Comments

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